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Parkinson’s disease, pesticide exposure

There has been a lot of research done in recent years that has exposed a strong link between pesticide exposure and the development of Parkinson’s disease. And now new research has added to that, showing that a pesticide discontinued from use in the U.S. ten years ago, benomyl, is still having a profound effect on the health of many people in the United States.

“Even more significantly, the research suggests that the damaging series of events set in motion by benomyl may also occur in people with Parkinson’s disease who were never exposed to the pesticide, according to Jeff Bronstein, senior author of the study and a professor of neurology at UCLA, and his colleagues.”

“Benomyl exposure, they say, starts a cascade of cellular events that may lead to Parkinson’s. The pesticide prevents an enzyme called ALDH (aldehyde dehydrogenase) from keeping a lid on DOPAL, a toxin that naturally occurs in the brain. When left unchecked by ALDH, DOPAL accumulates, damages neurons and increases an individual’s risk of developing Parkinson’s.”

Read the rest of the article here.

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